When exposed to an immune system that has received a COVID-19 vaccine, the presence of the L452R mutation in the coronavirus has been shown to reduce - by threefold - the effectiveness of antibodies to prevent the entry of viruses into the body's cells, Pinsky said. One reason Lambda has attracted attention is that it has a mutation known as L452Q, which is similar to a mutation known as L452R that has been found in the Delta variant and the so-called California variant, also known as the Epsilon variant, Pinsky said. So far, the Centers for Disease Control and Prevention has not named Lambda a variant of interest or concern in the United States - and cases are not being publicly tracked on the agency's website. “There are several mutations in the Lambda variant in the spike protein, there are some amino acid deletions, there's a number of characteristics of it that caused some concern because, of course, any changes in the virus pose some threat to its ability for the vaccines to work,” she said during a briefing. It is one that we are actively discussing and we are actively trying to gather and garner as much information as we can from all available sources,” said Maria Van Kerkhove, WHO’s technical lead for COVID-19. That’s not to say Lambda “is less important, by any means. Lambda is instead in a lower tier - a variant "of interest" - that the WHO considers worth watching but is of less concern for now. "But we don't know at the moment whether this will be something that will supplant Delta," he said in an interview.ĭespite its growing prominence in the public consciousness, Lambda isn't considered a variant "of concern," according to the World Health Organization - a designation reserved for the Alpha, Beta, Gamma and Delta coronavirus strains, which were first identified in Britain, South Africa, Brazil and India, respectively.
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